Utilizing melt extrusion technology
Microfluidizer
The core technology of the microfluidic high-pressure homogenizer is the precise integration of its fixed-geometry interaction chamber with an ultra-highpressure, stable boosting system. Utilizing controllable, repeatable, and efficient physical forces (shear, impact, cavitation), it delivers an exceptionally reliable and efficient nano-preparation platform solution for users, spanning from laboratory research and development to large-scale production.
successful processing in a single pass
seamless scalability
Core Components and Technical Principles
The “Y” type chamber is better suited for processing liquid-liquid systems, including emulsification, drug encapsulation, and liposome preparation.
The “Z” type chamber is more appropriate for handling solid-liquid systems such as cell disruption, nano-dispersion, deagglomeration, particle size reduction, and mechanical exfoliation.
Scalable from Lab to Production
| Maximum Throughput | Minimum Throughput | Maximum Pressure | Voltage & Power |
|---|---|---|---|
| 3–8 L/H | 15 ml | 200 MPa | 380 V / 2.5 kW |
| Maximum Throughput | Minimum Throughput | Maximum Pressure | Voltage & Power |
|---|---|---|---|
| 20,30,60 L/H | 200 ml | 200-276 MPa | 380 V / 4 kW,7.5KW,11KW |
| Maximum Throughput | Minimum Throughput | Maximum Pressure | Voltage & Power |
|---|---|---|---|
| 120,240,480 L/H | 5 L | 200 MPa | 380 V / 18 kW,35 KW,55 KW |
| Model | Flow Rate |
|---|---|
| 75Y | 3-5L/H @2000bar |
|
75Y/Z75 |
6-10L/H @2000bar |
| 75Y-2/Z100 |
25-30L/H@2000bar |
|
75Y-6/Z200 |
100-120L/H@2000bar |
|
100Y-6/Z400 |
240-480L/H@2000bar |
| Z300/Z400/Z700 | 30-480L/H |
DIAMOND INTERACTION CHAMBER
Primarily classified into two types: Y” type and “Z” type (designated for their internal diamond channels featuring fixed “Y” or “Z” shaped geometries). The internal microchannels do not vary with reaction conditions, ensuring consistent treatment performance for each 1ml of material passing through the chamber per pulse, high reproducibility across pulses, and a narrower particle size distribution in the processed material.
Y-type Homogenizing Chamber
Z-type Homogenizing Chamber
Product Advantages
Nano-scale Particle Size with Ultra-Narrow Distribution
Stable, consistent production of sub-100 nm formulations with a narrow particle size distribution.
Exceptional Process Repeatability and Scalability
Seamless scale-up from lab to industrial production, minimizing scale-up risks and production time.
High Efficiency and High Throughput
Single-pass processing for high efficiency and continuous industrial production.
Versatility Across Sample Types
Versatile applications across pharmaceuticals, biotechnology, cosmetics, food, and chemical industries.
Both laboratory-scale and production-scale models employ an identical core interaction chamber technology. This enables the optimal process parameters (primarily operating pressure) established on laboratory-scale units to be directly transferred to large-scale production equipment without re-optimization, thereby significantly reducing industrialization risks, costs, and development timelines.
Product Quality Index
Energy Generation
EXPERIMENTAL CASE
Liposome preparation
Particle size measurement after liposome preparation: 50–100 nm
Collagen preparation
Cerium Oxide
Cerium Oxide
